Vyvgrat is a biologic therapy that is indicated to treat for used to treat generalized myasthenia gravis (gMG).
Myasthenia gravis is an autoimmune disease that causes weakness in skeletal muscles, particularly after periods of activity. Symptoms may improve after a period of rest. While manageable with current treatments, myasthenia gravis can be accompanied by severe complications due to muscle weakness, such as respiratory failure.
gMG is thought to be caused by an overactive immune response related to Immunoglobulin G (IgG), the most common antibody.
When IgG starts working against your body, it turns into an AChR antibody. When this happens AChR targets receptors in the muscle that allows the brain to communicate with your muscular system, which results in the symptoms experienced in people suffering from gMg.
Vyvgart combats AChR antibodies by blocking Fc receptor (FcRn) which plays a role in controlling the number of antibodies released into your bloodstream, preventing an overreactive immune response.
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Once a week for 4 weeks
Before your infusion, it is important to drink plenty of water and come to your appointment hydrated. Additionally, you must alert us as soon as possible to any changes in your insurance to ensure that we are still an in-network provider for your infusion therapy.