What is Tepezza?

Tepezza is a biologic drug that is the first and only FDA-approved medication used to treat thyroid eye disease (TED). 

Behind your eyes there are tissues with cells that have receptors on their surface that act like light switches. When you have TED your body’s immune system attacks this tissue which causes molecules known as auto antibodies to turn these switches on.  

This leads to swelling to the muscle and fat. This in turn causes eye pain, redness around the eyes, and swollen eyelids. The swollen muscle and fat tissue behind the eye can make eyes bulge and cause double vision.  

Tepezza is designed to bind to the switch and block it from staying on. The two main mediators in TED are thyroid stimulating hormone receptor (TSHR) and insulin growth like factor 1 receptor (IGFR-1).   

In TED autoantibodies activate the IGFR-1R and TSHR signaling complex which stimulate orbital fibroblasts. Orbital fibroblasts are thought to be the cause of the severe inflammation and expansion of muscle and fat behind the eye. Tepezza blocks the IGFR 1R. 

What does Tepezza Treat?

  • Thyroid Eye Disease

Side Effects

  • Infusion reactions
  • Muscle spasm
  • Nausea
  • Hair loss
  • High blood sugar
  • Fatigue
  • Changes in taste
  • Dry Skin
Click here for additional side effects

Infusion Duration

60 to 90 minutes

Infusion Cycle

Once every 3 weeks for a total of 8 infusions

What to Expect During Your Infusion

Before your infusion, it is important to drink plenty of water and come to your appointment hydrated. Additionally, you must alert us as soon as possible to any changes in your insurance to ensure that we are still an in-network provider for your infusion therapy.

  1. Your dedicated Infusion nurse will check your vitals and review your medical history to check for improvements or potential side effects of your infusion therapy. 
  2. Your nurse will begin your infusion and check in on you periodically during your treatment. 
  3. After your infusion, your nurse will monitor you for 30 minutes to ensure you do not have any complications or reactions to the infusion therapy. 

Why patients choose Pure to receive their Tepezza infusion

At Pure Infusion Suites®, we create an unmatched patient experience, improve healthcare outcomes and lower the cost of care.

Safe & Private Suites

  • Comfortable, private rooms with a relaxing, spa-like atmosphere
  • 55” TVs with Netflix, Wifi, drinks, snacks, meals & more

Expert Medical Staff

  • Certified FNPs & infusion nurses on-site
  • Insurance pre-authorizations & re-authorizations
  • Patient lab work

Patient Assistance

  • Co-pay assistance & other financial aid programs
  • Flexible scheduling
  • Easy & convenient parking

Patient Stories

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