15 Feb Briumvi
Briumvi
What is Briumvi?
Briumvi (ublituximab-xiiy), is a biologic infusion used to treat relapsing forms of multiple sclerosis (MS), an autoimmune disease that predominantly affects the brain and spinal column.
In people with MS, their own immune system (B-lymphocytes) attack the myelin sheath, which is the protective covering on nerve cells in the central nervous system. When these B-cells are being produced, they have a CD20 marker which helps to identify them.
As the myelin sheath erodes, nerve cells become damaged, preventing them from communicating and sending signals to each other. Over time, this can affect motor skills, speech, bowel function, balance, and vision.
Briumvi is not a cure for MS, however, it is able to target the CD20 marker on B lymphocytes to destroy them so they can no longer harm the nerve cells. This is a way of suppressing the body’s overactive immune response.
What does Briumvi treat?
Multiple sclerosis of:
- Clinically isolated syndrome
- Relapsing-remitting disease
- Active secondary progressive disease
Side Effects
Most Common:
- Infusion reactions
- Upper respiratory tract infections
Others include:
- Bacterial and viral infections
- Fever
- Nausea
- Flu-type symptoms
- Throat irritation
- Flushing
- Hepatitis B reactivation
- Progressive Multifocal Leukoencephalopathy (PML) is possible but has not been observed.
Click here for additional side effects
Infusion Duration
1 to 4 hours
Infusion Cycle
1st and 2nd infusion 15 days apart. Then every 24 weeks.
What to Expect During Your Infusion
Before your infusion, it is important to drink plenty of water and come to your appointment hydrated. Additionally, you must alert us as soon as possible to any changes in your insurance to ensure that we are still an in-network provider for your infusion therapy.
- Your dedicated Infusion nurse will check your vitals and review your medical history to check for improvements or potential side effects of your infusion therapy.
- Your nurse will begin your infusion and check in on you periodically during your treatment.
- After your infusion, your nurse will monitor you for 30 minutes to ensure you do not have any complications or reactions to the infusion therapy.
Why patients choose Pure to receive their Briumvi infusion:
Safe & Private Suites
- Comfortable, private rooms with a relaxing, spa-like atmosphere
- 55” TVs with Netflix, Wifi, drinks, snacks, meals & more
Expert Medical Staff
- Certified FNPs & infusion nurses on-site
- Insurance pre-authorizations & re-authorizations
- Patient lab work
Patient Assistance
- Co-Pay assistance & other financial aid programs
- Flexible scheduling
- Easy & convenient parking
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